Non-contact monitoring of skin perfusion as a proxy for haemodynamic status
<p>The examination of skin perfusion is a key component of haemodynamic assessment. The body is quick to redirect blood flow away from the skin during periods of haemodynamic instability, making it a sensitive site for an early detection of cardiovascular compromise. The clinical assessment of...
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2023
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| _version_ | 1797110965553070080 |
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| author | Harford, M |
| author2 | Watkinson, P |
| author_facet | Watkinson, P Harford, M |
| author_sort | Harford, M |
| collection | OXFORD |
| description | <p>The examination of skin perfusion is a key component of haemodynamic assessment. The body is quick to redirect blood flow away from the skin during periods of haemodynamic instability, making it a sensitive site for an early detection of cardiovascular compromise. The clinical assessment of skin perfusion is mostly subjective. As an external organ, however, it is possible to objectively assess skin perfusion using video cameras operating both within and outside the visible light spectrum.</p>
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<p>The use of video cameras in clinical monitoring has been explored in vital-sign estimation, and may offer both objectivity and higher sensitivity compared to the current subjective assessment of skin perfusion. However, its evolution as a monitor has been held back by practical challenges such as vulnerability to signal noise from movement and lighting changes. This thesis describes the Mapping Of Lower Limb skIn pErfusion (MOLLIE) study, in which phenylephrine and glyceryl trinitrate (GTN) were used to pharmacologically induce skin perfusion changes in healthy volunteers under controlled environmental conditions. The participants were monitored using a variety of video cameras.</p>
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<p>Using this dataset, several streams of analyses are presented. First, image processing techniques are used to quantify clinically visible skin mottling. Following the measurement of these direct correlates of visually detected clinical findings, the remainder of the thesis demonstrates the detection of induced skin vasoconstriction and vasodilation which is not readily visible to the naked eye. A differential response to perfusion changes in different regions of skin is described, related to the underlying vascular anatomy of the skin.</p>
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<p>This thesis argues that video cameras can provide additional insight into the haemodynamic status. It is only by combining the knowledge of skin as an organ and its blood supply with the available image processing techniques that we can fully understand the information present in the measured parameters at the skin surface and improvements can be made in skin perfusion monitoring.</p> |
| first_indexed | 2024-03-07T08:02:03Z |
| format | Thesis |
| id | oxford-uuid:644047da-3c7f-49b5-9ebc-f19a0acd78b3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:02:03Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | oxford-uuid:644047da-3c7f-49b5-9ebc-f19a0acd78b32023-10-06T11:40:26ZNon-contact monitoring of skin perfusion as a proxy for haemodynamic statusThesishttp://purl.org/coar/resource_type/c_db06uuid:644047da-3c7f-49b5-9ebc-f19a0acd78b3EnglishHyrax Deposit2023Harford, MWatkinson, PTarassenko, L<p>The examination of skin perfusion is a key component of haemodynamic assessment. The body is quick to redirect blood flow away from the skin during periods of haemodynamic instability, making it a sensitive site for an early detection of cardiovascular compromise. The clinical assessment of skin perfusion is mostly subjective. As an external organ, however, it is possible to objectively assess skin perfusion using video cameras operating both within and outside the visible light spectrum.</p> <br> <p>The use of video cameras in clinical monitoring has been explored in vital-sign estimation, and may offer both objectivity and higher sensitivity compared to the current subjective assessment of skin perfusion. However, its evolution as a monitor has been held back by practical challenges such as vulnerability to signal noise from movement and lighting changes. This thesis describes the Mapping Of Lower Limb skIn pErfusion (MOLLIE) study, in which phenylephrine and glyceryl trinitrate (GTN) were used to pharmacologically induce skin perfusion changes in healthy volunteers under controlled environmental conditions. The participants were monitored using a variety of video cameras.</p> <br> <p>Using this dataset, several streams of analyses are presented. First, image processing techniques are used to quantify clinically visible skin mottling. Following the measurement of these direct correlates of visually detected clinical findings, the remainder of the thesis demonstrates the detection of induced skin vasoconstriction and vasodilation which is not readily visible to the naked eye. A differential response to perfusion changes in different regions of skin is described, related to the underlying vascular anatomy of the skin.</p> <br> <p>This thesis argues that video cameras can provide additional insight into the haemodynamic status. It is only by combining the knowledge of skin as an organ and its blood supply with the available image processing techniques that we can fully understand the information present in the measured parameters at the skin surface and improvements can be made in skin perfusion monitoring.</p> |
| spellingShingle | Harford, M Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title | Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title_full | Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title_fullStr | Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title_full_unstemmed | Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title_short | Non-contact monitoring of skin perfusion as a proxy for haemodynamic status |
| title_sort | non contact monitoring of skin perfusion as a proxy for haemodynamic status |
| work_keys_str_mv | AT harfordm noncontactmonitoringofskinperfusionasaproxyforhaemodynamicstatus |