Towards the synthesis and delivery of a halogenated MCT1 substrate

<p>The monocarboxylate transporter 1 (MCT1) has received special attention as a potential therapeutic target in cancer thanks to its role in lactate shuttling. In breast cancer (BC), high MCT1 expression has been correlated with basal-like phenotype and a ‘triple-negative’ status, an aggressiv...

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Bibliographic Details
Main Author: Skaripa-Koukelli, Eirini
Other Authors: Vallis, K
Format: Thesis
Language:English
Published: 2019
Subjects: