A timing-of-birth effect on multiple sclerosis clinical phenotype.
BACKGROUND: A month-of-birth (MOB) effect has been shown in multiple sclerosis (MS). METHODS: Our chi(2) analyses looked at whether this MOB effect differed by MS phenotype ("bout onset," "primary progressive"). RESULTS: The MOB effect was derived from "bout onset" MS...
मुख्य लेखकों: | , , , , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2007
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_version_ | 1826275994685669376 |
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author | Sadovnick, A Duquette, P Herrera, B Yee, I Ebers, G |
author_facet | Sadovnick, A Duquette, P Herrera, B Yee, I Ebers, G |
author_sort | Sadovnick, A |
collection | OXFORD |
description | BACKGROUND: A month-of-birth (MOB) effect has been shown in multiple sclerosis (MS). METHODS: Our chi(2) analyses looked at whether this MOB effect differed by MS phenotype ("bout onset," "primary progressive"). RESULTS: The MOB effect was derived from "bout onset" MS patients (May/November ratio = 1.43; chi(2) = 17.32, df = 1, p = 0.000032). CONCLUSIONS: An unspecified environmental effect in early development can influence both multiple sclerosis susceptibility and phenotype. |
first_indexed | 2024-03-06T23:07:18Z |
format | Journal article |
id | oxford-uuid:6448ca3e-f205-4dc3-a3a4-2d6f8d8ac4b2 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T23:07:18Z |
publishDate | 2007 |
record_format | dspace |
spelling | oxford-uuid:6448ca3e-f205-4dc3-a3a4-2d6f8d8ac4b22022-03-26T18:18:00ZA timing-of-birth effect on multiple sclerosis clinical phenotype.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6448ca3e-f205-4dc3-a3a4-2d6f8d8ac4b2EnglishSymplectic Elements at Oxford2007Sadovnick, ADuquette, PHerrera, BYee, IEbers, G BACKGROUND: A month-of-birth (MOB) effect has been shown in multiple sclerosis (MS). METHODS: Our chi(2) analyses looked at whether this MOB effect differed by MS phenotype ("bout onset," "primary progressive"). RESULTS: The MOB effect was derived from "bout onset" MS patients (May/November ratio = 1.43; chi(2) = 17.32, df = 1, p = 0.000032). CONCLUSIONS: An unspecified environmental effect in early development can influence both multiple sclerosis susceptibility and phenotype. |
spellingShingle | Sadovnick, A Duquette, P Herrera, B Yee, I Ebers, G A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title | A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title_full | A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title_fullStr | A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title_full_unstemmed | A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title_short | A timing-of-birth effect on multiple sclerosis clinical phenotype. |
title_sort | timing of birth effect on multiple sclerosis clinical phenotype |
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