Crystallization and X-ray diffraction analysis of human CLEC5A (MDL-1), a dengue virus receptor

The human C-type lectin-like protein CLEC5A (also known as MDL-1) is expressed on the surface of myeloid cells and plays a critical role in dengue-virus-induced disease by signalling through the transmembrane adaptor protein DAP12. The C-type lectin-like domain of CLEC5A was expressed in Escherichia...

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Main Authors: Watson, A, Ocallaghan, C
格式: Journal article
語言:English
出版: 2009