The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals.
The HIV-1 regulatory proteins Rev and Tat are expressed early in the virus life cycle and thus may be important targets for the immune control of HIV-1-infection and for effective vaccines. However, the extent to which these proteins are targeted in natural HIV-1 infection as well as precise epitope...
Main Authors: | Addo, M, Altfeld, M, Rosenberg, E, Eldridge, R, Philips, M, Habeeb, K, Khatri, A, Brander, C, Robbins, G, Mazzara, G, Goulder, P, Walker, B |
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Format: | Journal article |
Language: | English |
Published: |
2001
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