The immunological synapse: a molecular machine controlling T cell activation.

The specialized junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central cluster of T cell receptors surrounded by a ring of adhesion molecules. Immunological synapse formation is now shown to be an active and dynamic mechanism that allows T ce...

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Bibliographic Details
Main Authors: Grakoui, A, Bromley, S, Sumen, C, Davis, M, Shaw, A, Allen, P, Dustin, M
Format: Journal article
Language:English
Published: 1999