INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects.
AIMS: To elucidate the relationship between the human insulin gene INS VNTR regulatory polymorphism and insulin secretion. The polymorphism arises from tandem repetition of 14-15 bp oligonucleotides. In Caucasians, repeat number varies from 26 to over 200, with two main and discrete allele size clas...
Hlavní autoři: | Ahmed, S, Bennett, S, Huxtable, S, Todd, J, Matthews, DR, Gough, S |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1999
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