INS VNTR allelic variation and dynamic insulin secretion in healthy adult non-diabetic Caucasian subjects.
AIMS: To elucidate the relationship between the human insulin gene INS VNTR regulatory polymorphism and insulin secretion. The polymorphism arises from tandem repetition of 14-15 bp oligonucleotides. In Caucasians, repeat number varies from 26 to over 200, with two main and discrete allele size clas...
| Auteurs principaux: | , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
1999
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