Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction.

Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction.

Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the...

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Príomhchruthaitheoirí:	Beguerisse-Díaz, M, Desikan, R, Barahona, M
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Royal Society 2016

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