Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction.

Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Beguerisse-Díaz, M, Desikan, R, Barahona, M
التنسيق: Journal article
اللغة:English
منشور في: Royal Society 2016