Glycoviruses: chemical glycosylation retargets adenoviral gene transfer.
A sugar-specific transfection mechanism is introduced by the glycosylation of adenoviruses (AVs, see picture), and manipulation of the glycosylation pattern allows the selective transfection of human macrophages in favor of the usual target. This dramatic retargeting holds promise for the fine-tunin...
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Journal article |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
2005
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| _version_ | 1826276074584014848 |
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| author | Pearce, O Fisher, K Humphries, J Seymour, L Smith, A Davis, B |
| author_facet | Pearce, O Fisher, K Humphries, J Seymour, L Smith, A Davis, B |
| author_sort | Pearce, O |
| collection | OXFORD |
| description | A sugar-specific transfection mechanism is introduced by the glycosylation of adenoviruses (AVs, see picture), and manipulation of the glycosylation pattern allows the selective transfection of human macrophages in favor of the usual target. This dramatic retargeting holds promise for the fine-tuning of adenoviruses for applications such as gene therapy. © 2005 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim. |
| first_indexed | 2024-03-06T23:08:31Z |
| format | Journal article |
| id | oxford-uuid:64aca517-1cb3-4e57-8b08-e195baafa719 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:08:31Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:64aca517-1cb3-4e57-8b08-e195baafa7192022-03-26T18:20:27ZGlycoviruses: chemical glycosylation retargets adenoviral gene transfer.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:64aca517-1cb3-4e57-8b08-e195baafa719EnglishSymplectic Elements at Oxford2005Pearce, OFisher, KHumphries, JSeymour, LSmith, ADavis, BA sugar-specific transfection mechanism is introduced by the glycosylation of adenoviruses (AVs, see picture), and manipulation of the glycosylation pattern allows the selective transfection of human macrophages in favor of the usual target. This dramatic retargeting holds promise for the fine-tuning of adenoviruses for applications such as gene therapy. © 2005 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim. |
| spellingShingle | Pearce, O Fisher, K Humphries, J Seymour, L Smith, A Davis, B Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title | Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title_full | Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title_fullStr | Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title_full_unstemmed | Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title_short | Glycoviruses: chemical glycosylation retargets adenoviral gene transfer. |
| title_sort | glycoviruses chemical glycosylation retargets adenoviral gene transfer |
| work_keys_str_mv | AT pearceo glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer AT fisherk glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer AT humphriesj glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer AT seymourl glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer AT smitha glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer AT davisb glycoviruseschemicalglycosylationretargetsadenoviralgenetransfer |