A reversible gene trap collection empowers haploid genetics in human cells.
Knockout collections are invaluable tools for studying model organisms such as yeast. However, there are no large-scale knockout collections of human cells. Using gene-trap mutagenesis in near-haploid human cells, we established a platform to generate and isolate individual 'gene-trapped cells&...
Main Authors: | Bürckstümmer, T, Banning, C, Hainzl, P, Schobesberger, R, Kerzendorfer, C, Pauler, F, Chen, D, Them, N, Schischlik, F, Rebsamen, M, Smida, M, Fece de la Cruz, F, Lapao, A, Liszt, M, Eizinger, B, Guenzl, P, Blomen, V, Konopka, T, Gapp, B, Parapatics, K, Maier, B, Stöckl, J, Fischl, W, Salic, S, Taba Casari, MR |
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Format: | Journal article |
Language: | English |
Published: |
2013
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