Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
Polycomb repressive complex 1 (PRC1) is an essential chromatin-based repressor of gene transcription. How PRC1 engages with chromatin to identify its target genes and achieve gene repression remains poorly defined, representing a major hurdle to our understanding of Polycomb system function. Here, w...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2021
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