Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Polycomb repressive complex 1 (PRC1) is an essential chromatin-based repressor of gene transcription. How PRC1 engages with chromatin to identify its target genes and achieve gene repression remains poorly defined, representing a major hurdle to our understanding of Polycomb system function. Here, w...

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書目詳細資料
Main Authors: Klose, RJ, Huseyin, M
格式: Journal article
語言:English
出版: Springer Nature 2021