Structure of human complement C8, a precursor to membrane attack

Structure of human complement C8, a precursor to membrane attack

Weitere Versionen anzeigen (2)

Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Bubeck, D, Roversi, P, Donev, R, Morgan, B, Llorca, O, Lea, S
Format:	Journal article
Sprache:	English
Veröffentlicht:	2011

Ähnliche Einträge

Structure of human complement C8, a precursor to membrane attack.
von: Bubeck, D, et al.
Veröffentlicht: (2011)

Structure of human complement C8, a precursor to membrane attack
von: Bubeck, D, et al.
Veröffentlicht: (2011)

Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23 angstrom resolution
von: Roversi, P, et al.
Veröffentlicht: (2008)

Structural basis of complement membrane attack complex formation
von: Marina Serna, et al.
Veröffentlicht: (2016-02-01)

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
von: Hadders, M, et al.
Veröffentlicht: (2012)

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9.
von: Hadders, M, et al.
Veröffentlicht: (2012)

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
von: Michael A. Hadders, et al.
Veröffentlicht: (2012-03-01)

Structural analysis of the soluble C5b-9 complex using cryoelectron microscopy
von: Bubeck, D, et al.
Veröffentlicht: (2007)

Crystallisation and preliminary characterisation of crystals of complement component proteins
von: Roversi, P, et al.
Veröffentlicht: (2004)

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers
von: Anaïs Menny, et al.
Veröffentlicht: (2018-12-01)

Structure of the poly-C9 component of the complement membrane attack complex
von: Natalya V. Dudkina, et al.
Veröffentlicht: (2016-02-01)

Towards the crystal structure of human complement factor I
von: Roversi, P, et al.
Veröffentlicht: (2006)

Structural basis for recognition of the pore-forming toxin intermedilysin by human complement receptor CD59.
von: Johnson, S, et al.
Veröffentlicht: (2013)

Towards the crystal structure of intact Human Complement Factor I
von: Roversi, P, et al.
Veröffentlicht: (2009)

Crystallographic studies of human complement factor I
von: Roversi, P, et al.
Veröffentlicht: (2007)

Structure of and influence of a tick complement inhibitor on human complement component 5.
von: Fredslund, F, et al.
Veröffentlicht: (2008)

Structures of the rat complement regulator CrrY
von: Roversi, P, et al.
Veröffentlicht: (2011)

Structures of the rat complement regulator CrrY.
von: Roversi, P, et al.
Veröffentlicht: (2011)

Erratum: Structure of and influence of a tick complement inhibitor on human complement component 5.
von: Fredslund, F, et al.
Veröffentlicht: (2008)

Structural insights into complement function via studies of pathogen derived proteins
von: Roversi, P, et al.
Veröffentlicht: (2007)

Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59
von: Steven Johnson, et al.
Veröffentlicht: (2013-05-01)

Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8.
von: Prosser, B, et al.
Veröffentlicht: (2007)

Soluble Membrane Attack Complex: Biochemistry and Immunobiology
von: Scott R. Barnum, et al.
Veröffentlicht: (2020-11-01)

Structural basis for membrane attack complex inhibition by CD59
von: Emma C. Couves, et al.
Veröffentlicht: (2023-02-01)

Structural basis of soluble membrane attack complex packaging for clearance
von: Anaïs Menny, et al.
Veröffentlicht: (2021-10-01)

Structure of and influence of a tick complement inhibitor on human complement component 5 (vol 9, pg 753, 2008)
von: Fredslund, F, et al.
Veröffentlicht: (2008)

Distribution of protectin (CD59), a complement membrane attack inhibitor, in normal human tissues.
von: Meri, S, et al.
Veröffentlicht: (1991)

Active Human Complement Reduces the Zika Virus Load via Formation of the Membrane-Attack Complex
von: Britta Schiela, et al.
Veröffentlicht: (2018-10-01)

Structural basis for complement Factor I control and its disease associated sequence polymorphisms
von: Johnson, S, et al.
Veröffentlicht: (2011)

Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
von: Tsiftsoglou, SA, et al.
Veröffentlicht: (2006)

Structural views of complement protein interactions
von: Roversi, P, et al.
Veröffentlicht: (2004)

An inhibitor of complement C5 provides structural insights into activation
von: Reichhardt, M, et al.
Veröffentlicht: (2019)

The structure of OMCI, a novel lipocalin inhibitor of the complement system.
von: Roversi, P, et al.
Veröffentlicht: (2007)

Structural basis for complement factor I control and its disease-associated sequence polymorphisms
von: Roversi, P, et al.
Veröffentlicht: (2011)

Structural basis for complement factor I control and its disease-associated sequence polymorphisms.
von: Roversi, P, et al.
Veröffentlicht: (2011)

Complement in Human Pre-implantation Embryos: Attack and Defense
von: Martin P. Reichhardt, et al.
Veröffentlicht: (2019-09-01)

The crystal structure of rat complement receptor 1-related protein Y (CrrY) helps dissecting decay-acceleration and fI-cofactor activities
von: Roversi, P, et al.
Veröffentlicht: (2008)

The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
von: Charles Bayly-Jones, et al.
Veröffentlicht: (2023-01-01)

The membrane attack complex as an indicator of complement hyperactivation in type 2 diabetes mellitus
von: Elina Alexandrovna Arakelova, et al.
Veröffentlicht: (2011-09-01)

Quantitative Analysis of Complement Membrane Attack Complex Proteins Associated with Extracellular Vesicles
von: Illarion V. Turko
Veröffentlicht: (2024-07-01)