Structure of human complement C8, a precursor to membrane attack
Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...
Egile Nagusiak: | Bubeck, D, Roversi, P, Donev, R, Morgan, B, Llorca, O, Lea, S |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2011
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Antzeko izenburuak
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Structure of human complement C8, a precursor to membrane attack.
nork: Bubeck, D, et al.
Argitaratua: (2011) -
Structure of human complement C8, a precursor to membrane attack
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Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23 angstrom resolution
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Structural basis of complement membrane attack complex formation
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Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
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