Potent T cell agonism mediated by a very rapid TCR/pMHC interaction.
The interaction between T cell receptors (TCR) and peptide-major histocompatibility complex (pMHC) antigens can lead to varying degrees of agonism (T cell activation), or antagonism. The P14 TCR recognises the lymphocytic choriomeningitis virus (LCMV)-derived peptide, gp33 residues 33-41 (KAVYNFATC)...
Huvudupphovsmän: | , , , , , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2007
|