Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.

Míreanna comhchosúla

• Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.
  de réir: Sieber, O, et al.
  Foilsithe / Cruthaithe: (2004)
• Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas.
  de réir: Jones, A, et al.
  Foilsithe / Cruthaithe: (2007)
• Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.
  de réir: Lamlum, H, et al.
  Foilsithe / Cruthaithe: (2000)
• APC mutations are sufficient for the growth of early colorectal adenomas.
  de réir: Lamlum, H, et al.
  Foilsithe / Cruthaithe: (2000)
• Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
  de réir: Sieber, O, et al.
  Foilsithe / Cruthaithe: (2002)