DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication.
Nitric oxide (NO) is a very effective radiosensitizer of hypoxic mammalian cells, at least as efficient as oxygen in enhancing cell death in vitro. NO may induce cell death through the formation of base lesions which are difficult to repair, and if they occur within complex clustered damage common t...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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