Asymmetric syntheses of (- )-hastanecine, (- )-turneforcidine and (- )-platynecine

Asymmetric syntheses of (- )-hastanecine, (- )-turneforcidine and (- )-platynecine

Concise total asymmetric syntheses of three diastereoisomeric 1-hydroxymethyl-7-hydroxy substituted pyrrolizidines, (−)-hastanecine, (−)-turneforcidine and (−)-platynecine, are reported. The doubly diastereoselective conjugate additions of lithium (R)- or (S)-N-benzyl-N-(α-methylbenzyl)amide to tert...

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Detalles Bibliográficos
Main Authors:	Davies, S, Brambilla, M, Fletcher, A, Roberts, P, Thomson, J
Formato:	Journal article
Publicado:	Elsevier 2016

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