Cancer stem cells versus phenotype-switching in melanoma.
Tumours comprise multiple phenotypically distinct subpopulations of cells, some of which are proposed to possess stem cell-like properties, being able to self-renew, seed and maintain tumours, and provide a reservoir of therapeutically resistant cells. Here, we use melanoma as a model to explore the...
Main Authors: | Hoek, K, Goding, C |
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Format: | Journal article |
Language: | English |
Published: |
2010
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