Cancer stem cells versus phenotype-switching in melanoma.

Tumours comprise multiple phenotypically distinct subpopulations of cells, some of which are proposed to possess stem cell-like properties, being able to self-renew, seed and maintain tumours, and provide a reservoir of therapeutically resistant cells. Here, we use melanoma as a model to explore the...

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Autori principali: Hoek, K, Goding, C
Natura: Journal article
Lingua:English
Pubblicazione: 2010