APC mutations are sufficient for the growth of early colorectal adenomas.

It is not clear whether APC mutations are sufficient for early colorectal adenomas to grow or whether additional mutations at other loci are required. We previously have screened 210 early colorectal adenomas from familial adenomatous polyposis patients for mutations and allelic loss at APC. Here, w...

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Hlavní autoři: Lamlum, H, Papadopoulou, A, Ilyas, M, Rowan, A, Gillet, C, Hanby, A, Talbot, I, Bodmer, W, Tomlinson, I
Médium: Journal article
Jazyk:English
Vydáno: 2000