Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

Inappropriate activation or inadequate regulation of CD4+ and CD8+ T cells may contribute to the initiation and progression of multiple autoimmune and inflammatory diseases. Studies on disease-associated genetic polymorphisms have highlighted the importance of biological context for many regulatory...

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Bibliographic Details
Main Authors: Kasela, S, Kisand, K, Tserel, L, Kaleviste, E, Remm, A, Fischer, K, Esko, T, Westra, H, Fairfax, B, Makino, S, Knight, J, Franke, L, Metspalu, A, Peterson, P, Milani, L
Format: Journal article
Language:English
Published: Public Library of Science 2017

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