Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.

Aggrecanases have been characterized as proteinases that cleave the Glu373-Ala374 bond of the aggrecan core protein, and they are multidomain metalloproteinases belonging to the ADAMTS (adamalysin with thrombospondin type 1 motifs) family. The first aggrecanases discovered were ADAMTS-4 (aggrecanase...

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Hlavní autoři: Gendron, C, Kashiwagi, M, Lim, N, Enghild, J, Thøgersen, I, Hughes, C, Caterson, B, Nagase, H
Médium: Journal article
Jazyk:English
Vydáno: 2007