The vacuolar pathway of long peptide cross-presentation can be TAP dependent

The intracellular pathway of cross-presentation, which allows MHC class I–restricted presentation of peptides derived from exogenous Ags, remains poorly defined and may vary with the nature of the exogenous Ag and the type of APC. It can be cytosolic, characterized by proteasome and TAP dependency,...

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Bibliographic Details
Main Authors: Ma, W, Stroobant, V, Heirman, C, Sun, Z, Thielemans, K, Mulder, A, Van Der Bruggen, P, Van Den Eynde, B
Format: Journal article
Language:English
Published: American Association of Immunologists 2019