Adeno-associated virus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor reduces atherosclerotic lesion formation in LDL receptor knockout mice.

Macrophage scavenger receptors (MSR) promote atherosclerotic lesion formation, and modulation of MSR activity has been shown to influence atherosclerosis. Soluble receptors are effective in inhibiting receptor-mediated functions in various diseases. We have generated a secreted macrophage scavenger...

詳細記述

書誌詳細
主要な著者: Jalkanen, J, Leppänen, P, Pajusola, K, Närvänen, O, Mähönen, A, Vähäkangas, E, Greaves, D, Büeler, H, Ylä-Herttuala, S
フォーマット: Journal article
言語:English
出版事項: 2003