Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix
The membrane-anchored collagenase membrane type 1 matrix metalloprotease (MT1-MMP) has been shown to play an essential role during epithelial tubulogenesis in 3D collagen matrices; however, its regulation during tubulogenesis is not understood. Here, we report that degradation of collagen in polariz...
Main Authors: | Weaver, SA, Wolters, B, Ito, N, Woskowicz, A, Kaneko, K, Shitomi, Y, Seiki, M, Itoh, Y |
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Format: | Journal article |
Language: | English |
Published: |
Company of Biologists
2014
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