Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor.

OBJECTIVE: To assess the effect of the downregulation of type 1 insulin-like growth factor receptor (IGF1R) on the chemosensitivity of prostate cancer cells. IGF1R is overexpressed by prostate cancer compared with benign prostatic epithelium and IGF1R expression commonly persists in androgen-indepen...

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Bibliographic Details
Main Authors: Hellawell, G, Ferguson, D, Brewster, S, Macaulay, V
Format: Journal article
Language:English
Published: 2003