Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.

BACKGROUND: Genetic studies have provided ample evidence of the influence of non-coding DNA polymorphisms on trait variance, particularly those occurring within transcription factor binding sites. Protein binding microarrays and other platforms that can map these sites with great precision have enha...

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Detalhes bibliográficos
Principais autores: Wong, D, Teixeira, A, Oikonomopoulos, S, Humburg, P, Lone, I, Saliba, D, Siggers, T, Bulyk, M, Angelov, D, Dimitrov, S, Udalova, I, Ragoussis, J
Formato: Journal article
Idioma:English
Publicado em: 2011