Mechanistic pathways underlying altered neurovascular coupling in brain metastasis

Objectives: It is recognised that astrocytes form a physical bridge between neurons and the cerebrovasculature. Astrocytic end-feet help maintain endothelial tight junctions to support the blood–brain barrier (BBB) and release vasoactive molecules that regulate vascular tone. In secondary cancer (me...

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Main Authors: Sarmiento Soto, M, Serres, S, Bristow, C, Economopoulos, V, Larkin, J, Escartin, C, Bonvento, G, Sibson, N
格式: Conference item
出版: SAGE Publications 2016