Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides

Enantioselective rhodium-catalysed insertion of trifluorodiazoethanes into tin hydrides

Aryl substituted 2,2,2-trifluorodiazoethanes undergo rhodium(II)-catalysed insertion reactions with tin hydrides affording the corresponding α-(trifluoromethyl)benzyl stannanes. This reactivity contrasts with that of diazo esters which predominantly afford CH2 reduction products in the presence of t...

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书目详细资料
Main Authors: Hyde, S, Veliks, J, Ascough, D, Szpera, R, Paton, R, Gouverneur, V
格式: Journal article
语言:English
出版: Elsevier 2018
实物特征
总结:Aryl substituted 2,2,2-trifluorodiazoethanes undergo rhodium(II)-catalysed insertion reactions with tin hydrides affording the corresponding α-(trifluoromethyl)benzyl stannanes. This reactivity contrasts with that of diazo esters which predominantly afford CH2 reduction products in the presence of tin hydrides. The first example of asymmetric insertion into tin hydrides using diazo compounds is also described. In addition, this system extends to asymmetric germanium hydride and silane insertion.

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