Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions...
Main Authors: | Borghini, L, Png, E, Binder, A, Wright, V, Pinnock, E, De Groot, R, Hazelzet, J, Emonts, M, Van Der Flier, M, Schlapbach, L, Anderson, S, Secka, F, Salas, A, Fink, C, Carrol, E, Pollard, A, Coin, L, Kuijpers, T, Martinon-Torres, F, Zenz, W, Levin, M, Hibberd, M, Davila, S, Euclids Consortium |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Springer Nature
2019
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