Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood.
Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase activity and hence PG production. However, the ability of NSAIDs to ameliorate pain and tenderness does not prevent disease progression in rheumatoid arthritis, a disease whose pathogenesis is linked to the presence of proinflammat...
Hauptverfasser: | Page, T, Turner, J, Brown, A, Timms, E, Inglis, J, Brennan, F, Foxwell, B, Ray, K, Feldmann, M |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2010
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