The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

Fundamental to cell adhesion and migration, integrins are large heterodimeric membrane proteins that uniquely mediate inside-out signal transduction, whereby adhesion to the extracellular matrix is activated from within the cell by direct binding of talin to the cytoplasmic tail of the beta integrin...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Anthis, N, Wegener, K, Ye, F, Kim, C, Goult, B, Lowe, E, Vakonakis, I, Bate, N, Critchley, DR, Ginsberg, M, Campbell, I
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2009

Samankaltaisia teoksia