Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele.

INTRODUCTION: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder caused by mutations in desmosomal genes. It is often associated with life-threatening arrhythmias. Some affected individuals develop progressive heart failure and may require cardiac transplantation. METHODS:...

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Hlavní autoři: Gehmlich, K, Syrris, P, Reimann, M, Asimaki, A, Ehler, E, Evans, A, Quarta, G, Pantazis, A, Saffitz, J, McKenna, W
Médium: Journal article
Jazyk:English
Vydáno: 2012