Nuclear entry and export of FIH are mediated by HIF1α and exportin1 respectively
Hypoxia plays a critical role at cellular and physiological levels in all animals. The responses to chronic hypoxia are, at least substantially, orchestrated by activation of the hypoxia inducible transcription factors (HIFs), whose stability and subsequent transcriptional activation are regulated t...
Principais autores: | Wang, Y, Zhong, S, Schofield, C, Ratcliffe, P, Lu, X |
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Formato: | Journal article |
Publicado em: |
Company of Biologists
2018
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