Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

Themis (thymocyte-expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis had high expression in thymocytes between the pre-T cell antigen receptor (pre-TCR) and positive-selection checkpoint...

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Bibliographic Details
Main Authors: Fu, G, Vallée, S, Rybakin, V, McGuire, M, Ampudia, J, Brockmeyer, C, Salek, M, Fallen, P, Hoerter, J, Munshi, A, Huang, Y, Hu, J, Fox, H, Sauer, K, Acuto, O, Gascoigne, N
Format: Journal article
Language:English
Published: 2009

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