A proteomic analysis of changes in prothrombin and plasma proteins associated with the G20210A mutation.
The G-->A mutation at position 20210 of the prothrombin gene, localized in the 3'-polyadenylation untranslated region of the mRNA, is a recognized genetic risk factor for venous thromboembolism. The mechanism by which this base change confers an increased risk of thrombosis compared to n...
Main Authors: | Gelfi, C, Viganò, A, Ripamonti, M, Wait, R, Begum, S, Biguzzi, E, Castaman, G, Faioni, E |
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Format: | Journal article |
Language: | English |
Published: |
2004
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