CRISPR-Cas gene perturbation and editing in human induced pluripotent stem cells

Directing the fates of human pluripotent stem cells (hPSC) to generate a multitude of differentiated cell types allows the study of the genetic regulation of human development and disease. The translational potential of hPSC is maximized by exploiting CRISPR to silence or activate genes with spatial...

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Hlavní autoři: van Essen, M, Riepsaame, J, Jacob, J
Médium: Journal article
Jazyk:English
Vydáno: Mary Ann Liebert 2021