FORMATION OF A NOVEL BICYCLIC GAMMA-LACTAM WITH ISOPENICILLIN-N SYNTHASE

Incubation of isopenicillin N synthase (IPNS) with [(5S)-5-amino-5- carboxypentanoyl]-L- homocysteinyl-L-cysteine (14) resulted in the formation of a novel bicyclic γ-lactam (17) containing an intramolecular disulphide linkage.

Détails bibliographiques
Auteurs principaux:	Baldwin, J, Blackburn, J, Sako, M, Schofield, C
Format:	Journal article
Langue:	English
Publié:	1989

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