Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone.

Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone.

OBJECTIVE: Clinicians have few evidence-based options for the management of treatment-resistant bipolar depression. This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentati...

Full description

Bibliographic Details
Main Authors:	Nierenberg, A, Ostacher, M, Calabrese, JR, Ketter, T, Marangell, L, Miklowitz, D, Miyahara, S, Bauer, MS, Thase, M, Wisniewski, SR, Sachs, G
Format:	Journal article
Language:	English
Published:	2006

Similar Items

Lamotrigine treatment of bipolar disorder: data from the first 500 patients in STEP-BD.
by: Marangell, L, et al.
Published: (2004)

Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
by: Perlis, R, et al.
Published: (2006)

Are antidepressants associated with new-onset suicidality in bipolar disorder? A prospective study of participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
by: Bauer, MS, et al.
Published: (2006)

Effectiveness of adjunctive antidepressant treatment for bipolar depression.
by: Sachs, G, et al.
Published: (2007)

Clinical features associated with poor pharmacologic adherence in bipolar disorder: results from the STEP-BD study.
by: Perlis, R, et al.
Published: (2010)

Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD.
by: Goldberg, J, et al.
Published: (2009)

Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study.
by: Perlis, R, et al.
Published: (2009)

Benzodiazepine use and risk of recurrence in bipolar disorder: a STEP-BD report.
by: Perlis, R, et al.
Published: (2010)

Adjunctive antidepressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: findings from the STEP-BD.
by: Goldberg, J, et al.
Published: (2007)

The prospective course of rapid-cycling bipolar disorder: findings from the STEP-BD.
by: Schneck, C, et al.
Published: (2008)

Demographic and diagnostic characteristics of the first 1000 patients enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
by: Kogan, J, et al.
Published: (2004)

Safety and Tolerability Associated with Second Generation Antipsychotic Polytherapy in Bipolar Disorder: Findings from STEP-BD
by: Brooks, J, et al.
Published: (2009)

Validity of the distinction between primary and secondary substance use disorder in patients with bipolar disorder: data from the first 1000 STEP-BD participants.
by: Fossey, MD, et al.
Published: (2006)

Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD.
by: Goldberg, J, et al.
Published: (2009)

Association between therapeutic alliance, care satisfaction, and pharmacological adherence in bipolar disorder.
by: Sylvia, L, et al.
Published: (2013)

Psychosocial service utilization by patients with bipolar disorders: data from the first 500 participants in the Systematic Treatment Enhancement Program.
by: Lembke, A, et al.
Published: (2004)

Transition to mania during treatment of bipolar depression.
by: Perlis, R, et al.
Published: (2010)

Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial.
by: Miklowitz, D, et al.
Published: (2007)

Intensive psychosocial intervention enhances functioning in patients with bipolar depression: Results from a 9-month Randomized controlled trial
by: Miklowitz, D, et al.
Published: (2007)

Correlates of functioning in bipolar disorder.
by: Gyulai, L, et al.
Published: (2008)

Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program.
by: Miklowitz, D, et al.
Published: (2007)

Perceived criticism from family members as a predictor of the one-year course of bipolar disorder.
by: Miklowitz, D, et al.
Published: (2005)

Contributors to suicidal ideation among bipolar patients with and without a history of suicide attempts.
by: Allen, M, et al.
Published: (2005)

Lamotrigine and lithium as maintenance treatment for bipolar I disorder
by: Yatham, L, et al.
Published: (2004)

Safety and tolerability associated with second-generation antipsychotic polytherapy in bipolar disorder: findings from the Systematic Treatment Enhancement Program for Bipolar Disorder.
by: Brooks, J, et al.
Published: (2011)

Correlates of functioning in bipolar disorder.
by: Gyulai, L, et al.
Published: (2008)

Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the Systematic Treatment Enhancement Program.
by: Schneck, C, et al.
Published: (2004)

Dysfunctional Attitudes, Attributional Styles, and Phase of Illness in Bipolar Disorder
by: Reilly-Harrington, N, et al.
Published: (2010)

Sleep matters: sleep functioning and course of illness in bipolar disorder.
by: Gruber, J, et al.
Published: (2011)

Sleep matters: Sleep functioning and course of illness in bipolar disorder
by: Gruber, J, et al.
Published: (2011)

Factors associated with stigma among caregivers of patients with bipolar disorder in the STEP-BD study.
by: Gonzalez, J, et al.
Published: (2007)

Prospective 12-month course of bipolar disorder in out-patients with and without comorbid anxiety disorders.
by: Otto, M, et al.
Published: (2006)

Correlates of subjective and objective burden among caregivers of patients with bipolar disorder.
by: Ostacher, M, et al.
Published: (2008)

Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 years.
by: Marangell, L, et al.
Published: (2006)

Lamotrigine in the treatment of bipolar disorder.
by: Bhagwagar, Z, et al.
Published: (2005)

Age at onset, course of illness and response to psychotherapy in bipolar disorder: results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
by: Peters, A, et al.
Published: (2014)

Do comorbid anxiety disorders moderate the effects of psychotherapy for bipolar disorder? Results from STEP-BD.
by: Deckersbach, T, et al.
Published: (2014)

Glycemic equipoise
by: Sanjay Kalra, et al.
Published: (2017-01-01)

Caregiver burden and health in bipolar disorder: a cluster analytic approach.
by: Perlick, D, et al.
Published: (2008)

Age at onset, course of illness and response to psychotherapy in bipolar disorder: Results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
by: Peters, A, et al.
Published: (2014)