A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

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Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to define the transcriptional program underlying angiogenesis in human cancer. This approach identified ELTD1, an orphan...

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Hlavní autoři: Masiero, M, Simões, F, Han, H, Snell, C, Peterkin, T, Bridges, E, Mangala, L, Wu, S, Pradeep, S, Li, D, Han, C, Dalton, H, Lopez-Berestein, G, Tuynman, J, Mortensen, N, Li, J, Patient, R, Sood, A, Banham, A, Harris, A, Buffa, F
Médium: Journal article
Jazyk:English
Vydáno: 2013

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