The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.

The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.

Infection with the hepatitis C virus (HCV) has a huge impact on global health putting more than 170 million people at risk of developing severe liver disease. The HCV encoded p7 ion channel is essential for the production of infectious viruses. Despite a growing body of functional data, little is kn...

Descripció completa

Dades bibliogràfiques
Autors principals:	Luik, P, Chew, C, Aittoniemi, J, Chang, J, Wentworth, P, Dwek, R, Biggin, P, Vénien-Bryan, C, Zitzmann, N
Format:	Journal article
Idioma:	English
Publicat:	National Academy of Sciences 2009

Ítems similars

The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein
per: Whitfield, T, et al.
Publicat: (2011)

Deciphering the Relationship Between Hepatitis C Virus (HCV) P7 and Its Foes
per: Chew, C, et al.
Publicat: (2010)

Protein-protein interactions: modeling the hepatitis C virus ion channel p7.
per: Patargias, G, et al.
Publicat: (2005)

Determination of pore-lining residues in the hepatitis C virus p7 protein.
per: Chew, C, et al.
Publicat: (2009)

Use of iminosugar derivatives to inhibit ion channel activity
per: Zitzmann, N, et al.
Publicat: (2004)

The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives.
per: Pavlović, D, et al.
Publicat: (2003)

Modeling of an ion channel in its open conformation.
per: Domene, C, et al.
Publicat: (2005)

Long alkylchain iminosugars block the HCV p7 ion channel
per: Pavlovic, D, et al.
Publicat: (2005)

Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles.
per: Fotinou, C, et al.
Publicat: (2013)

Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles
per: Fotinou, C, et al.
Publicat: (2013)

Protein structure determination by electron cryo-microscopy.
per: Jonic, S, et al.
Publicat: (2009)

Direct visualization of KirBac3.1 potassium channel gating by atomic force microscopy.
per: Jarosławski, S, et al.
Publicat: (2007)

Simulation approaches to ion channel gating
per: Biggin, P, et al.
Publicat: (2002)

The Hepatitis C Virus E2p7 localization and topology in a recombinant system
per: Popescu, C, et al.
Publicat: (2009)

Defect imaging and channeling studies using channeling scanning transmission ion microscopy
per: King, P, et al.
Publicat: (1996)

Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.
per: Aittoniemi, J, et al.
Publicat: (2009)

Ion channel gating: insights via molecular simulations.
per: Beckstein, O, et al.
Publicat: (2003)

Cryo–electron microscopy unveils the gating mechanism of the human Kir2.1 channel
per: Venien-Bryan Catherine, et al.
Publicat: (2024-01-01)

Simulation approaches to ion channel structure-function relationships.
per: Tieleman, D, et al.
Publicat: (2001)

Water in ion channels and pores--simulation studies.
per: Sansom, MS, et al.
Publicat: (2002)

Sugar immunogens
per: Dwek, R, et al.
Publicat: (2009)

Projection structure of a transcriptional regulator, HupR, determined by electron cryo-microscopy.
per: Vénien-Bryan, C, et al.
Publicat: (2000)

Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker
per: Gangadharan, B, et al.
Publicat: (2012)

Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
per: Gangadharan, B, et al.
Publicat: (2008)

Potassium and sodium ions in a potassium channel studied by molecular dynamics simulations.
per: Biggin, P, et al.
Publicat: (2001)

Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7
per: Walter, S, et al.
Publicat: (2016)

Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
per: Gangadharan, B, et al.
Publicat: (2010)

The open state of KirBac3.1 observed by cryo-electron microscopy
per: Zadek, B, et al.
Publicat: (2007)

K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study.
per: Shrivastava, I, et al.
Publicat: (2002)

DISLOCATION IMAGING WITH A SCANNING PROTON MICROPROBE USING CHANNELING SCANNING-TRANSMISSION ION MICROSCOPY (CSTIM)
per: King, P, et al.
Publicat: (1993)

Novel serum biomarker candidates for liver fibrosis in hepatitis C patients
per: Gangadharan, B, et al.
Publicat: (2007)

Synthesis of a hemifluorinated amphiphile designed for self-assembly and two-dimensional crystallization of membrane protein
per: Dauvergne, J, et al.
Publicat: (2008)

Role of aromatic localization in the gating process of a potassium channel.
per: Domene, C, et al.
Publicat: (2006)

Role of aromatic localization in the gating process of a potassium channel.
per: Domene, C, et al.
Publicat: (2006)

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane.
per: Marc A Dämgen, et al.
Publicat: (2021-02-01)

Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.
per: Chapel, C, et al.
Publicat: (2006)

Use of castanospermine and substituted-castonospermine compounds for treating hepatitis virus infections
per: Jacob, G, et al.
Publicat: (2001)

The p7 protein of hepatitis C virus forms structurally plastic, minimalist ion channels.
per: Danielle E Chandler, et al.
Publicat: (2012-01-01)

Mechanosensitive channels: stress relief.
per: Biggin, P, et al.
Publicat: (2003)

Channel gating: twist to open.
per: Biggin, P, et al.
Publicat: (2001)