Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.

Detaylı Bibliyografya
Asıl Yazarlar:	Alp, N, Mussa, S, Khoo, J, Cai, S, Guzik, T, Jefferson, A, Goh, N, Rockett, K, Channon, K
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2003

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Endothelial-targeted GTP cyclohydrolase I overexpression increases endothelial tetrahydrobiopterin levels and preserves eNOS coupling in eNOS overexpressing mice
Yazar:: Bendall, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
Yazar:: Bendall, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
Yazar:: Wang, W, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Yazar:: Chuaiphichai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
Yazar:: Chuaiphichai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
Yazar:: Tatham, A, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Yazar:: Chuaiphichai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Yazar:: Cai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
Yazar:: Chuaiphichai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
Yazar:: Du, Y, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
Yazar:: Du, Y, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
Yazar:: Chen, A, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
Yazar:: Cai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
Yazar:: Chen, A, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
Yazar:: Adlam, D, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
Yazar:: Carnicer, R, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
Yazar:: Liao, S, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats.
Yazar:: Meininger, C, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
Yazar:: Cai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation
Yazar:: Cai, S, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
Yazar:: Carnicer, R, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Increased endothelial tetrahydrobiopterin levels in GTPCH-transgenic mice
Yazar:: Alp, N, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

PRESERVATION OF ENDOTHELIAL GTP CYCLOHYDROLASE I ACTIVITY AND IMPROVEMENT OF RENAL NITRIC OXIDE AVAILABILITY PREVENT THE DEVELOPMENT OF DIABETIC NEPHROPATHY
Yazar:: Satoh, M, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
Yazar:: Adlam, D, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
Yazar:: Crabtree, M, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
Yazar:: Khoo, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
Yazar:: Adlam, D, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
Yazar:: Chen, A, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
Yazar:: Carnicer, R, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
Yazar:: Du, Y, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
Yazar:: Antoniades, C, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.

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