Chapter 5 Long-Range Regulation of α-Globin Gene Expression

Chapter 5 Long-Range Regulation of α-Globin Gene Expression

Over the past 20 years, there has been an increasing awareness that gene expression can be regulated by multiple cis-acting sequences located at considerable distances (10-1000 kb) from the genes they control. Detailed investigation of a few specialized mammalian genes, including the genes controlli...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Higgs, D, Vernimmen, D, Wood, B
Format:	Książka
Wydane:	2008

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The transcriptional regulation of the zeta-globin gene
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Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
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ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
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ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression.
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The α-globin super-enhancer acts in an orientation-dependent manner
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Conservation of position and sequence of a novel, widely expressed gene containing the major human alpha-globin regulatory element.
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Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin.
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Molecular rearrangements of the human alpha-globin gene cluster.
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The mouse alpha-globin locus regulatory element.
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Identification of a conserved erythroid specific domain of histone acetylation across the a globin gene cluster.
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Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster.
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The 5' flanking region of human epsilon-globin gene.
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5' structural motifs and Xenopus beta globin gene activation.
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