High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure
BACKGROUND:Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available. A Plasmodium falciparum phenotype with delayed parasite clearance during artemisinin-based combination therapy has established in Southeast Asia...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2018
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