tidal breathing model of the forced inspired inert gas sinewave technique

We have shown previously that it is possible to assess the cardio-respiratory function using sinusoidally oscillating inert gas forcing signals of nitrous oxide and argon (Hahn et al., 1993). This method uses an extension of a mathematical model of respiratory gas exchange introduced by Zwart et al....

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Bibliographic Details
Main Authors: Gavaghan, D, Hahn, C
Format: Journal article
Published: 1996
Description
Summary:We have shown previously that it is possible to assess the cardio-respiratory function using sinusoidally oscillating inert gas forcing signals of nitrous oxide and argon (Hahn et al., 1993). This method uses an extension of a mathematical model of respiratory gas exchange introduced by Zwart et al. (1976), which assumed continuous ventilation. We investigate the effects of this assumption by developing a mathematical model using a single alveolar compartment and incorporating tidal ventilation, which must be solved using numerical methods. We compare simulated results from the tidal model with those from the