DNA hairpins primarily promote duplex melting rather than inhibiting hybridization

<p>The effect of secondary structure on DNA duplex formation is poorly understood. Using oxDNA, a nucleotide level coarse-grainedmodel of DNA, we study how hairpins influence the rate and reaction pathways of DNA hybridzation. We compare to experimental systems studied by Gao et al. and find t...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Schreck, J, Ouldridge, T, Romano, F, Sulc, P, Shaw, L, Louis, A, Doye, J
Formatua: Journal article
Argitaratua: 2014