Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Yolk sac (YS) hematopoiesis is critical for the survival of the embryo and a major source of tissue-resident macrophages that persist into adulthood. Yet, the transcriptional and epigenetic regulation of YS hematopoiesis remains poorly characterized. Here we report that the epigenetic regulator Ezh2...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Neo, WH, Meng, Y, Rodriguez-Meira, A, Fadlullah, MZH, Booth, CAG, Azzoni, E, Thongjuea, S, de Bruijn, MFTR, Jacobsen, SEW, Mead, AJ, Lacaud, G
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Springer Nature 2021